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Lung Cancer Animal Model (CAT#: STEM-AE-0089-WXH)

Introduction

Lung cancer accounts for 12.7% of tumor incidence and 18.2% of mortality in the world, and is currently one of the most common diseases causing death. Clinically and histopathologically, lung cancer is divided into two categories, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). In order to study lung cancer in depth, animal models are the basis of all research.




Applications

Research on the pathogenesis of lung cancer and drug development.

Procedure

• Inducible models: use chemical carcinogens to induce models.
• Portability model:
CDX (cell derived xenograft) model is a tumor model constructed by transplanting tumor cell lines into nude mice or NSG mice.
The PDX (patientl derived xenograft) model is to transplant tumor tissue into NSG mice in the form of tissue, thus maintaining the heterogeneity of the tumor well.
• Transgenic models: change the expression of oncogenes or tumor suppressor genes, including K-RAS gene mutation models, P53 gene mutation models, etc.

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