WeSPR Series MetaSPR

The WeSPR Series represents a new generation of label-free Surface Plasmon Resonance (SPR) instruments based on proprietary Meta-Surface Plasmon Resonance (MetaSPR) technology. Designed for high-sensitivity, high-throughput biomolecular interaction analysis, the WeSPR family includes multiple models tailored for different research and development needs, such as WeSPR One, WeSPR One Auto, WeSPR 100X, WeSPR 200, WeSPR HT8, WeSPR Imager, and WeSPR Cell Analyzer SP.

Together, these platforms provide flexible solutions for biomolecular research, discovery, and screening applications, supporting areas such as drug discovery, antibody development, vaccine research, and cellular biology.

What is MetaSPR Technology?

Diagram illustrating MetaSPR technology, showing how a light source and detector measure optical density changes on a 3D nanostructured metasurface chip to detect biomolecular interactions in real time. (STEMart Authorized)

MetaSPR (Meta-Surface Plasmon Resonance) is a next-generation nanoplasmonic detection technology that builds upon conventional SPR. Instead of traditional 2D film-based optical chips, MetaSPR employs 3D nanostructured metasurface chips, enabling detection of changes in optical density at specific wavelengths of transmitted light.

This innovation:

Enhances sensitivity, capturing subtle biomolecular interactions with greater precision.
Expands application range, making it suitable for complex biological and clinical samples.
Reduces operating and maintenance costs, delivering both performance and efficiency.

R-CLASS SPR System Applications (STEMart Original)

How It Works

The WeSPR series employs a fixed-angle light incidence design to monitor intensity changes at specific wavelengths within an absorption spectrum. When light illuminates the metasurface chip, the nanostructured metallic surface excites free electrons, generating plasmon resonance and secondary light emission.

Binding events at the chip surface alter the local refractive index, leading to measurable shifts in transmitted spectra. These shifts appear as decreases or increases in light intensity at particular wavelengths, producing real-time, label-free signals of molecular interactions.

Advantages of MetaSPR over Conventional SPR

High Sensitivity - Nanostructured metasurface chips, fabricated using photolithography, provide localized plasmonic enhancement and significantly improved detection sensitivity.

High Throughput - Unlike traditional angle-scanning SPR, MetaSPR employs spectral scanning across wide optical fields, breaking throughput limitations and enabling both high-throughput and high-precision analysis.

Broad Sample Compatibility - Reduced bulk effects improve tolerance to crude or complex biological samples, making it ideal for real-world R&D and translational applications.

Illustration showing how MetaSPR technology works - light beams striking a nanostructured metasurface chip to generate plasmon resonance for detecting biomolecular interactions. (STEMart Original)

Explore the WeSPR Product Line

WeSPR One Biomolecular Interaction Analyzer (STEMart Authorized)

WeSPR One Auto Biomolecular Interaction Analyzer (STEMart Authorized)

WeSPR 100X Multifunctional Molecular Detection System (STEMart Authorized)

WeSPR 200 Multifunctional Molecular Detection System (STEMart Authorized)

WeSPR One

WeSPR One Auto

WeSPR 100X

WeSPR 200

WeSPR HT8 Fully Automated Multifunctional Molecular Detection System (STEMart Authorized)

WeSPR Imager High-Throughput Imaging Molecular Interaction Analyzer (STEMart Authorized)

WeSPR Cell Analyzer SP Real-Time Label-Free Cellular Analysis System (STEMart Authorized)

WeSPR HT8

WeSPR Imager

WeSPR Cell Analyzer SP

From fundamental biomolecular research to biopharmaceutical discovery and development, the WeSPR Series delivers the performance, flexibility, and reliability you need.

Contact us today to learn more about the WeSPR Series, request detailed specifications, or arrange a demonstration tailored to your research needs.

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