Hydrogel‐based Embolic Agent Development Service

Embolization, a technique used to block blood flow to specific areas of the body, is widely employed in the treatment of various conditions, including tumors, aneurysms, and arteriovenous malformations. Among the many materials explored for embolization, hydrogels have emerged as a promising candidate due to their unique properties, such as biocompatibility, tunable mechanical strength, and controlled degradation. At STEMart, we offer specialized development services to support the design, testing, and optimization of hydrogel-based embolic agents. Our end-to-end solutions are designed to accelerate the development of innovative and effective embolic agents, ensuring they meet the highest standards of safety, efficacy, and regulatory compliance.

Schematic illustration of design of transarterial chemoembolization (TACE) agents.Fig.1 Schematic illustration of hydrogel‐based embolic agents.1

Hydrogel-based Embolic Agent Development Solution

STEMart provides a comprehensive suite of services designed to streamline the development of next-generation hydrogel-based embolic agents. Our expertise spans the entire development pipeline, from material synthesis and characterization to preclinical and regulatory support. We offer in-depth in vitro and in vivo testing, leveraging advanced imaging and analytical techniques to evaluate material performance and biocompatibility.

Material Selection and Formulation Optimization

STEMart offers a wide range of hydrogel materials for embolic agent development, including natural polymers and synthetic polymers such as polyethylene glycol (PEG). Our team can customize formulations to meet specific clinical requirements, including adjusting gelation time, mechanical properties, and biodegradability. Furthermore, we facilitate real-time procedural visualization by incorporating imaging agents, such as radiopaque materials, into our hydrogel formulations.

Prototype Fabrication

Our capabilities encompass the fabrication of hydrogel-based embolic agents in diverse forms, such as microspheres, injectable gels, or pre-formed implants. We also offer scalable production of prototypes, ensuring efficient progression from initial design to rigorous testing and evaluation.

In Vitro and In Vivo Testing

Our in vitro models simulate blood flow and vascular conditions to assess gelation, adhesion, and occlusion efficacy. For in vivo evaluation, we use animal models to study the embolic effects, biocompatibility, and long-term stability of the agents. We have extensive experience in conducting rigorous testing to ensure that our hydrogel-based embolic agents perform consistently and safely under a variety of conditions.

Why Partner with STEMart?

STEMart is a trusted partner in developing advanced medical materials and technologies. Our team of scientists, engineers, and regulatory experts is dedicated to delivering innovative solutions that meet the highest standards of quality and safety. By choosing STEMart for your hydrogel-based embolic agent development needs, you benefit from:

  • Expertise: Our team consists of experienced scientists and engineers with extensive knowledge in hydrogel development and vascular intervention.
  • Customization: We understand that every project has its own distinct requirements. Our services are tailored to meet your specific needs.
  • Quality: We ensure the highest standards in all our services, ensuring reliable and reproducible results.
  • Collaboration: We work closely with our clients to provide transparent communication and timely updates throughout the development process.

Contact us today to learn more about our hydrogel-based embolic agent development service and how we can support your research and development efforts.

Reference

  1. Chen, Yun-Ping, et al. "Recent advances on polymeric beads or hydrogels as embolization agents for improved transcatheter arterial chemoembolization (TACE)." Frontiers in chemistry 7 (2019): 408. Distributed under Open Access license CC BY 4.0, without modification.

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