On-chip Sort - STEMart

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On-chip Sort is a microfluidic-based cell sorter designed for gentle, high-precision droplet and cell sorting. It operates at low pressure (1.3 psi), eliminating shear stress and ensuring high cell viability, making it ideal for sensitive applications like single-cell analysis, microbial culturing, and rare cell isolation (e.g., circulating tumor cells, CTCs). Compatible with On-chip Droplet Generator, it enables fluorescence-activated sorting of water-in-oil droplets and gel microbeads, supporting workflows in cell development, drug discovery, and clinical research.

Why Choose On-chip Sort

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Versatile Sorting

Accommodate rare cell, cell clusters, droplet with encapsulated cells/microbials for diverse applications.

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Damage-Free Sorting

Unique flow shift sorting mechanism to prevent cell damages caused by high pressure, ultrasonic waves, electric charges, or reservoir collisions.
Flexible sheath fluids to prevent cell damages induced by osmotic pressure.
Less effect on cell proliferation, morphology, and gene expression.

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Multi-Step Sorting

Repeated gentle microfluidic separations to enable sequential purification of rare cells while maintaining cell viability.

Applications

Fluorescence-based sorting post-cultivation to select droplets with proliferated cells.
Screening environmental bacteria using fluorescent nucleic acid probes.
Repeated soring to enrich rare targets (e.g., CTCs) from bulk samples.
Sorting spheroids (cell clusters) of a particular size from a spheroid culture or clinical materials.

Specifications

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The On-Chip Sort leverages microfluidic chip, flow shift, and multistep sorting technology for easy, gentle, and efficient sorting of rare cells, large clusters, microbes, and droplets. This system can be widely used in biomedical research, industrial microbiology, and single-cell analysis. Contact STEMart to learn more details about On-chip Sort.

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