Suspended Microchannel Resonator (SMR) Technology

Suspended microchannel resonator (SMR) is a novel microfluidic microelectromechanical system which uses the principle that the resonating frequency of an oscillating cantilever (visualize a diving board in motion) is proportional to its mass. A Suspended microchannel resonator (SMR) is made up of a hollow resonant structure containing a tiny fluidics channel surrounded by a vacuum. When a single cell flows through the channel inside the cantilever, the resonant frequency of the cantilever changes in proportion to the mass of the cell. This technology can be used for a broad range biological application for measuring the mass, volume, density and size of polystyrene particles, Escherichia coli bacteria and human red blood cell.