On-chip Droplet Generator

The On-chip Droplet Generator utilizes a specialized microfluidic chip to produce large quantities of water-in-oil (W/O) emulsion droplets and gel microdrops (GMDs) at micrometer scales. These droplets serve as isolated microreactors for applications including microbial/cell culture and genetic analysis.

On-chip Droplet Generator acts as a prominent high-throughput screening tool that can be used for single cell analysis or simultaneous assay of more than 1 million samples.

Key Advantages

• Easy adjustment of droplet diameter (60–220 µm) via pressure regulation
• Mass generation (~100,000 droplets in minutes) of stable and monodisperse droplets
• Real-time monitoring of droplet generation with integrated monitoring device
• Precise adjustment of temperature (-5–70°C) for stable incubation via integrated temperature controller

Applications

Combined with On-chip Sort for automated droplet screening, On-chip Droplet Generator can be used for:

• Encapsulation and cultivation of a variety of microorganisms while maintaining high microbial diversity.
• Screening of highly productive strains via detection of enzymes/metabolites secreted in droplet.
• Development of stable and productive antibody-producing cell lines.
• Screening of difficult-to-cultivate microorganisms via detection of microbial proliferation.

Specifications

On-chip Droplet Generator is designed to create microenvironment within micro-scale aqueous droplets for encapsulation, isolation and cultivation of microorganisms and cells. It transforms how we culture microbes. Contact STEMart to learn more details about On-chip Droplet Generator.