WeSPR Imager High-Throughput Imaging Molecular Interaction Analyzer

WeSPR Imager

Visualizing Molecular Interactions

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The WeSPR Imager is a high-performance, high-throughput label-free imaging platform for real-time biomolecular interaction analysis. Leveraging proprietary Meta-Surface Plasmon Resonance (metaSPR) technology, the system detects binding and dissociation events directly on chip surfaces by monitoring changes in optical transmission patterns captured through an advanced microscopy system.

This imaging-based approach enables parallel characterization of small molecules, proteins, nucleic acids, antibodies, viruses, and even whole cells, making the WeSPR Imager an indispensable tool for life science research and pharmaceutical development.

Principle

When incident light illuminates a nanostructured metallic surface (such as gold or silver coating on glass), it excites free electron oscillations that generate resonance and secondary optical emission. These resonance effects produce characteristic transmission images. Any molecular binding or solution change on the chip surface alters the transmission image, which the WeSPR Imager captures in real time through its imaging system to quantify biomolecular interactions without labeling.

Features

Advanced Microfluidics: Eight parallel microfluidic channels combined with a precise spotting system enable up to 64 (8×8) detection sites simultaneously.

High-Sensitivity Imaging: Powerful imaging optics deliver superior sensitivity for diverse biomolecules, providing high-quality affinity and kinetic data.

Integrated Solution: Supports multiple analysis modes, including screening, characterization, epitope binning, and quantitation—covering key stages of drug discovery and development.

Broad Sample Compatibility: Capable of analyzing complex samples without preprocessing, expanding application range and reducing workflow bottlenecks.

Automated Operation: Large-capacity, low-temperature, anti-evaporation sample chamber with streamlined protocols enables up to 48 hours unattended operation.

Compliant Software Suite: Modular instrument control and data analysis software designed to meet GxP compliance requirements, ensuring suitability for regulated environments.

Specifications

The WeSPR Imager combines imaging-based metaSPR detection, high-throughput parallel analysis, and long-term automation into a single platform. By supporting 64 simultaneous detection points, high sensitivity, and complex sample compatibility, it offers unmatched performance for modern biopharmaceutical research. Its integrated, GxP-ready software and robust hardware design make it a powerful solution for both academic laboratories and industrial drug development pipelines.

Contact us today to learn how WeSPR Imager can enhance your molecular interaction analysis with high-throughput imaging precision.