Q Seplife A25 Strong Anion-Exchange Medium, 110 mg α-Lactalbumin/mL (CAT#: STEM-BC-3171-ZJF)

This strong anion-exchange medium is designed for downstream purification of proteins, nucleic acids, and peptides. It uses highly crosslinked dextran G25 as the supporting matrix. Trimethylaminoalkyl quaternary ammonium groups provide permanent anion-exchange functionality. The dry particles range from 40 to 120 µm. An α-lactalbumin adsorption capacity of 110 mg/mL supports preparative purification. The medium combines high flow with relatively low operating backpressure. Broad chemical stability permits use with common aqueous buffers and concentrated denaturants. The matrix tolerates the stated steam-treatment conditions in sodium chloride solution. Its scalable format can shorten processing time and reduce production costs.

Model: Q Seplife A25
Appearance: White powder, odorless and tasteless
Type: Strong anion-exchange medium
Matrix: Dextran G25
Ligand: Trimethylaminoalkyl quaternary ammonium salt
Dry particle size: 40-120 µm
α-Lactalbumin adsorption capacity: 110 mg/mL
Ion-exchange capacity: 2.6-3.4 mmol/g dry gel
Working pH range: 2-12
Long-term pH stability: 2-13
Short-term pH stability: 2-13
Chemical compatibility: Common aqueous buffers, 8 M urea, and 6 M guanidine hydrochloride
Heat resistance: 121°C in 0.1 M sodium chloride for 30 min

Strong quaternary-ammonium exchange
110 mg/mL protein capacity
Crosslinked dextran matrix
Broad pH stability
Denaturant-compatible operation
Steam-treatment tolerance
Low operating backpressure
Suitable for process scale-up

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