DNA sequencing by the scanning tunneling microscope (CAT#: STEM-MIT-0319-LJX)

Introduction

A revolutionary new microscope, the scanning tunneling microscope (STM), can image some surfaces at atomic resolution, even in air or water. It can produce high-resolution images of DNA. Studies have shown that STM can also be used for DNA sequencing.

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Principle Applications Procedure Materials Notes Related Products

Principle

The basic principle of scanning tunneling microscope (STM) is to use the tunneling effect in quantum theory. An extremely fine probe of atomic linearity and the surface of the substance under study are used as two electrodes. When the sample is very close to the tip of the needle (usually less than 1nm), electrons flow through the barrier between the two electrodes to the other electrode under the action of an applied electric field. This phenomenon is known as tunneling effect.

Applications

Studing the structure of the sample surface by high resolution imaging
Manipulating individual atoms to form nanostructures

Procedure

1. Sampling
2. Preparation of slices (Select according to the specific experimental situation)
3. Staining (Select according to the specific experimental situation)
4. Observation

Materials

• Sample Type:
Chromatin

Notes

Operate in strict accordance with the operating procedures, and shall not arbitrarily change the operating procedures

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