Study of chromosomes in spermatozoa of translocation carriers by Fluorescence in situ hybridisation (FISH) (CAT#: STEM-MB-1192-WXH)

Introduction

In the infertile male population, there is a 2–20-time higher probability of having a structural chromosomal abnormality than in general population. Generally, these men have a normal phenotype but they can have sperm abnormalities. As they can produce a variable proportion of unbalanced gametes, it is important to evaluate the percentage of unbalanced chromosomal spermatozoa to assess the risk of injecting a chromosomally unbalanced gamete during ICSI procedure.