DEAE Large Scale Weak Anion-Exchange Medium, 90 mg Ovalbumin/mL (CAT#: STEM-BC-3077-ZJF)

This weak anion-exchange medium is designed for downstream separation of proteins, nucleic acids, and peptides. It uses high-flow agarose microspheres functionalized with diethylaminoethyl groups. The highly crosslinked matrix provides chemical and mechanical stability. Large particles support high linear velocity with relatively low backpressure. The stated ovalbumin adsorption capacity supports productive biomolecule capture. Weak anion-exchange chemistry provides selectivity that differs from quaternary-amine media. Low nonspecific adsorption helps maintain product recovery. The medium supports cleaning with sodium hydroxide and exposure to common denaturants. Its scalable format can shorten processing time in manufacturing applications.

Model: DEAE Large Scale
Appearance: White spherical gel, odorless and tasteless
Type: Weak anion-exchange medium
Matrix: Large Scale microspheres
Ligand: Diethylaminoethyl
Particle size: 45-165 µm
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common aqueous buffers, 1 mol/L sodium hydroxide, 8 mol/L urea, 8 mol/L guanidine hydrochloride, and 70% ethanol
Adsorption capacity: 90 mg ovalbumin/mL
Ion-exchange capacity: 0.29-0.35 mmol/mL
Operating temperature: 4-40°C
Heat resistance: 121°C in water for 30 min
Flow performance: 700 cm/h at 20 cm bed height and 0.3 MPa

Weak anion-exchange selectivity
High ovalbumin capacity
700 cm/h flow performance
Low backpressure
Broad CIP pH range
Strong chemical stability
Low nonspecific adsorption
Suitable for process scale-up

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