Targeted region sequencing (TRS-seq） (CAT#: STEM-MB-0065-WXH)

Introduction

Targeted region sequencing (TRS-seq) is an effective approach for investigating your selected region(s) of interest by next generation sequencing. By utilizing targeted region sequencing panels, you can discover single-nucleotide polymorphisms (SNPs), insertions/deletions (InDels), copy number variations (CNVs), and structural variants (SVs). Compared with whole genome sequencing, targeted region sequencing enables accurate detection of rare variants with higher sensitivity and specificity. This approach is very cost-effective when handling a large number of samples, which significantly reduces the cost per sample.<br />Its sequencing principle is based on the principle of DNA hybridization, using probes customized for the target genomic region to perform chip hybridization or solution hybridization with genomic DNA, enriching the DNA in the target gene region, and then performing sequencing through NGS technology.