Dual RNA-seq to study interaction between two species (CAT#: STEM-MB-0076-WXH)

Introduction

There is a wide range of interactions between species, such as parasitism, symbiosis, competition, etc. The conventional transcriptome sequencing can only study the information of a single species, which not only wastes part of the data, but also affects the sample itself during the separation of two species.<br />Dual RNA-seq has been shown to monitor the all classes of coding and noncoding transcripts of both host and pathogen simultaneously. <br />By constructing only one transcriptome library, dual RNA-seq of total mixed RNA following double rRNA depletion or poly(A) capture allows sequencing and analyzing two (or more) species at the same time without the need to separate the species, thereby revealing the dynamic changes in gene expression between them.