Analysis of Superoxide dismutases (Cu, Zn) by Raman Spectroscopy (CAT#: STEM-ST-0013-WXH)

Introduction

Superoxide dismutases (Cu, Zn) are cystosolic enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. Thus, they are an important antioxidant defense in nearly all cells exposed to oxygen. SOD is composed of the protein (apoenzym) and a catalytic prosthetic group in the form of metal atom serving as the active center. The ligands of the copper and zinc ions are six histidine molecules and one aspartate side chains, where one histidine molecule is shared between the two metal ions.