Phospho-modified Proteomics (CAT#: STEM-MB-0093-WXH)

Introduction

Protein phosphorylation is the process of transferring the phosphate group of ATP to the amino acid residue (Ser, Thr, Tyr) of the substrate protein catalyzed by protein kinase, or binding to GTP under the action of a signal, which is a common regulation method in organisms. More than 30% of proteins in cells are phosphorylated, which plays an important role in cell signal transduction, regulation of cell proliferation, development, differentiation, and apoptosis. Protein phosphorylation is the most fundamental, pervasive, and most important mechanism for regulating and controlling protein activity and function.