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Peptidomics (CAT#: STEM-MB-0098-WXH)

Introduction

Peptidomics takes endogenous peptides and low-molecular-weight proteins of the body as the research object, and studies the structure, function, change rules and related relationships of the peptide group. There is no clear boundary between polypeptides and proteins, and proteins with a molecular weight of less than 10kDa are generally considered to be polypeptides. Peptidomics and proteomics are both supplements to genomics. Peptides can reflect the synthesis, processing and degradation of proteins under different physiological and pathological conditions, and at the same time regulate gene expression and substance metabolism. Therefore, peptidomics is considered as a "bridge" between proteomics and metabolomics.




Applications

• Identification of all expressed polypeptides in cells, tissues, and body fluid samples in a certain physiological state
• Biomarkers as novel diseases
• Neuropeptide/Signal Peptide Research
• Natural Antibacterial/Antiviral Peptides
• Cell Epitope Prediction
• Study on Catalytic Reaction of Unknown Enzyme in Vivo
• Development of novel peptide prodrugs
• Mining new functional peptide molecules

Procedure

1. Sample pretreatment
2. Isolation and enrichment of endogenous peptides
3. LC-MS/MS mass spectrometry detection
4. Search library for qualitative/Denovo analysis
5. Biological information analysis

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