Label-free quantitative proteomics (CAT#: STEM-MB-0086-WXH)

Introduction

Label-free quantification is a method in mass spectrometry that aims to determine the relative amount of proteins in two or more biological samples. Unlike other methods for protein quantification, label-free quantification does not use a stable isotope containing compound to chemically bind to and thus label the protein. <br />In principle, the label-free approach is based on peptide mass spectral peak intensity profiling. <br />A major advantage of label-free technology is that it allows the ligand to retain its native conformation and biological activity.