Asthma Animal Model (CAT#: STEM-AE-0053-WXH)

Introduction

Asthma is a chronic airway inflammatory disease characterized by variable airflow obstruction, airway hyperresponsiveness (AHR), and airway inflammation. The main clinical symptoms of asthma are shortness of breath, wheezing, coughing, and increased mucus secretion after exposure to allergens. Its pathogenesis is caused by a complex interplay between genetic, epigenetic and environmental factors.
The classic mouse asthma model is ovalbumin (OVA)-induced airway inflammation model. Mice are sensitized by intraperitoneal injection of OVA for many times, and stimulated after aerosol inhalation of OVA to establish an acute asthma model.