Acute Lung Injury Animal Model (CAT#: STEM-AE-0060-WXH)

Introduction

Acute lung injury (ALI) refers to a state of severe hypoxemia and respiratory distress caused by various reasons, which cannot be corrected even by conventional oxygen inhalation. When it is more severe, it is called acute respiratory distress syndrome. Acute lung injury usually results from diffuse capillary endothelial and alveolar epithelial damage after the body is severely injured. Patients may experience symptoms of chest pain, chest tightness, shortness of breath, and shortness of breath. If not controlled in time, the condition may gradually aggravate. In severe cases, hemoptysis, respiratory distress, respiratory failure, hypoxemia, hypercapnia, lethargy, coma, and even death may occur.

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Applications

• Study the pathogenesis and treatment of acute lung injury.
• Drug development, drug screening and efficacy research.

Procedure

• Endotoxin (lipopolysaccha-rides, LPS)-induced acute lung injury.
• Transfusion-induced acute lung injury.
• Acute lung injury from blunt impact.
• Ventilator-induced lung injury (VILI).
• Acute lung injury from ischemia-reperfusion.

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