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COPD Animal Model (CAT#: STEM-AE-0056-WXH)

Introduction

Chronic obstructive pulmonary disease (COPD) is a chronic bronchitis and/or emphysema characterized by airflow obstruction, which can further develop into a common chronic disease of pulmonary heart disease and respiratory failure. It is related to the abnormal inflammatory response of harmful gases and particles, and the disability rate and mortality rate are very high. The global incidence rate of over 40 years old has reached as high as 9% to 10%.




Applications

• To explore the pathogenesis of chronic obstructive pulmonary disease models.
• To evaluate the efficacy of drugs related to chronic obstructive pulmonary disease models.

Procedure

1. Anesthetize, slowly inject lipopolysaccharide solution into the trachea, and rotate the rat upright after the injection, so that the drug solution is evenly distributed in the lungs.
2. Passive smoking in the exposure box for 30 minutes every day.
3. Model verification and evaluation.

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