Integrin Signaling Pathway Assay (CAT#: STEM-MB-0337-WXH)

Introduction

Integrin, as a family of cell surface receptors, is a transmembrane glycoprotein widely distributed on the cell surface. It is a heterodimer composed of a and β subunits through non-covalent bonds, and is an important complication on the cell surface. Receptors with adhesion and signal transduction functions. By combining the extracellular domain with the extracellular matrix (cell-extra-cellular matrixECM), the intracellular domain and the signal transduction molecule, integrins mediate the two-way signal transduction between the inside and outside of the cell, and regulate the growth, differentiation, migration, and growth of cells. Migration, invasion, apoptosis, survival and proliferation, adhesion, differentiation and other aspects play an important role.