High Plus Maze (CAT#: STEM-AE-0009-WXH)

Introduction

High plus maze is to investigate the anxiety state of animals by using the animal's exploration characteristics of novel environments and the fear of high hanging arms to form conflicting behaviors.<br />The elevated plus maze has a pair of open arms and a pair of closed arms. Rodents tend to move in the closed arms due to their dark phobia, but move in the open arms because of curiosity and exploration. In the face of novel stimuli, animals have the impulse to explore and fear at the same time, which results in the conflict behavior of exploration and avoidance, resulting in anxiety. However, anti-anxiety drugs can significantly increase the number and time of entering the open arm, and the cross maze is higher than the ground, which is equivalent to a person standing on a cliff, causing fear and anxiety in the experimental subjects.