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Conditioned Place Preference Experiment (CAT#: STEM-AE-0006-WXH)

Introduction

In the Conditioned Place Preference (CPP) experiment, the experimental animals (rats, mice) were placed in the white observation area of the conditioned place preference box, and were given psychotropic drugs (such as morphine).<br />Then observe the activity of the experimental animals in the black area and white area of the conditioned place preference box. Every time the animal is in the drug administration area, it will have a positional preference for the black and white areas under the action of the rewarding effect of the drug, and the degree is related to the psychological dependence of the drug.




Applications

The classic experimental model for evaluating psychotropic drug dependence is also an effective tool widely used to find anti-drug-seeking behaviors.

Procedure

1. Pretreatment to Familiarize Animals with the Apparatus.
2. Put the animal into a box after injecting the drug, repeat several times.
3. Preference experiment: Remove the partitions between the boxes and observe the time the animals stay in each box.

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