Recombinant Human KGF (FGF-7) Protein, Seafrom (CAT#: STEM-CT-0049-ZJF)

The Recombinant Human KGF (FGF-7) Protein manufactured by Seafrom is suitable for promoting epithelial cell proliferation and tissue repair.
KGF/FGF-7 is one of the 23 known members of the FGF (fibroblast growth factor) family. Proteins in this family play a central role in prenatal development, postnatal growth, and tissue regeneration by promoting cell proliferation and differentiation. KGF/FGF-7 is a mitogenic factor specific to epithelial cells and keratinocytes. The signaling of KGF/FGF-7 occurs through FGFR 2b. KGF/FGF-7 plays a critical role in kidney and lung development, as well as in angiogenesis and wound healing.
The lyophilized formulation can be stored at 4°C for 24 months. Once reconstituted, the liquid can be stored at -20°C for 6-12 months, avoiding repeated freeze-thaw cycles.

Expression Host: Human HEK293 Cells
Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
Protein Sequence: DNA sequence encodes human KGF (NP_002000.1) with an Fc tag at the C-terminus, contains 292 amino acids, predicted molecular weight of 45.6 kD
Purity: ≥95%, analyzed by SDS-PAGE and HPLC
Endotoxin Level: <0.1 EU/μg
Biological Activity: ED50 determined by 4MBr-5 cynomolgus monkey epithelial cell proliferation assay is 20-100 ng/mL
Purification Method: Chromatographic purification
Appearance: White loose body

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

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