Photoacoustic Imaging (PAI) (CAT#: STEM-PET-0013-WXH)

Briefly, the technique detects endogenous or exogenous chromophores that are excited through an illumination carried out with pulsed laser light, typically in the Red-NIR range. The non-radiative release of the absorbed energy produces a microheating and a thermoelastic expansion in the chromophore close surrounding, which can generate ultrasound. The acoustic waves are detected by a transducer and transformed into an image.

• Oncology (cancer detection, assessment of vascular volume and hypoxia, targeting experiments, assessment of drug distribution and therapy outcome)
• Neurobiology (stroke, brain cancer, intracranial injection of drugs, functional imaging)
• Cardiovascular biology (heart attack, detection of atherosclerotic plaques, hemodynamic and O2 perfusion)
Developmental biology (vascular volume and oxygenation of placenta, image-guided embryo injection, fetal analysis)
• Abdomen analysis (kidney diseases as renal microcirculation flow, renal obstruction analysis, gastrointestinal motility, organs’ perfusion)
• Skin analysis (mainly detection of melanin in melanoma cells)
• Image-guided injection of drug