Endometriosis Animal Model (CAT#: STEM-AE-0071-WXH)

Introduction

Endometriosis (Ems) refers to the location of endometrial glands and stromal tissue outside the normal endometrial position, affecting 6% to 10% of women of childbearing age. Ectopic endometrial tissue is mainly found on the peritoneal surface, ovary, and rectovaginal septum. Ems outside the pelvis are rare, and the abdominal wall is the most common site of Ems outside the pelvis.

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Principle Applications Procedure Materials Notes Related Products

Applications

• Research on the mechanism and treatment of endometriosis.
• Research on etiology of EMs, drug trials, hormone regulation, etc.

Procedure

• Autologous transplantation model: Transplant autologous uterine tissue or endometrium to the ovary, uterosacral ligament, serosal layer of the posterior wall of the lower uterine segment, and pelvic peritoneum covering the uterine rectal lacuna and sigmoid colon through surgery (equivalent to human heterogeneous The common site of intima) can induce the model to occur.
• Allograft model: A model of endometriosis produced by transplanting human endometrium or ectopic tissue into immunodeficient animals.

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