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Kidney disease is very common clinically, and changes in kidney function are closely related to the cardiovascular system. Whether it is primary glomerular disease, diabetes or ureteral obstruction, renal function damage is closely related to the degree of renal fibrosis. The unilateral ureteral obstruction (UUO) model is an ideal pathological model for imitating human obstructive nephropathy, and is often used in the study of the mechanism of renal fibrosis.
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