Seplife LXPM SP 5504M Strong Cation-Exchange Medium, 300-1000 cm/h (CAT#: STEM-BC-3099-ZJF)

This strong cation-exchange medium is designed for high-throughput capture and purification of biological macromolecules. It uses a polymethyl methacrylate matrix with a hydrophilic surface treatment. Strong sulfonic-acid functional groups provide cation-exchange binding. The 80 µm particles support higher flow rates while maintaining packed-bed stability. A 1000 Å pore size provides access for antibodies, proteins, peptides, oligonucleotides, viruses, and insulin. The rigid matrix resists compression and supports operation at elevated linear velocities. Low nonspecific adsorption helps maintain product recovery during repeated cycles. The medium is compatible with acids, bases, and a broad range of listed organic solvents.

Model: Seplife® LXPM SP 5504M
Matrix: Polymethyl methacrylate
Appearance: White opaque spherical particles
Functional group: -O-R-O-(CH2)3-SO3-
Ion-exchange type: Strong cation exchange
Exchange capacity: 0.13-0.17 mmol/mL
Average particle size: 80 µm
Pore size: 1000 Å
Binding capacity: ≥110 mg lysozyme/mL
Pressure-flow range: 300-1000 cm/h at 22 mm × 20 cm bed and 3 bar
Compression factor: ≤1.05
Maximum pressure: 0.8 MPa
Storage solution: 20% ethanol with stated sodium chloride preservative
Regeneration: 0.5-2 M sodium chloride
Cleaning: 0.1-0.5 M sodium hydroxide or 50% ethanol
Solvent stability: Resistant to acids, alkalis, methanol, ethanol, toluene, DMSO, DMF, and n-heptane

High 300-1000 cm/h flow
≥110 mg/mL lysozyme capacity
Strong sulfonic-acid functionality
Low compression factor
High mechanical strength
Broad organic-solvent resistance
Low nonspecific adsorption
Designed for large-scale purification

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