Seplife LXPM Q 5504M Strong Anion-Exchange Medium, ≥95 mg BSA/mL (CAT#: STEM-BC-3100-ZJF)

This strong anion-exchange chromatography medium is designed for capture, intermediate purification, and polishing applications. It uses a polymethyl methacrylate matrix with a hydrophilic surface modification. Quaternary amine groups provide strong anion-exchange functionality. The 80 µm particles support high flow and stable packed-bed operation. A 1000 Å pore structure accommodates antibodies, proteins, peptides, nucleic acids, viruses, and insulin. The rigid polymeric matrix provides strong mechanical stability and low compression. Low nonspecific adsorption supports product recovery and reproducible purification. The medium tolerates acids, bases, and the listed organic solvents during compatible process operations.

Model: Seplife® LXPM Q 5504M
Matrix: Polymethyl methacrylate
Appearance: White opaque spherical particles
Functional group: -O-R-N+-(CH3)3
Ion-exchange type: Strong anion exchange
Exchange capacity: 0.08-0.12 mmol/mL
Average particle size: 80 µm
Pore size: 1000 Å
Binding capacity: ≥95 mg BSA/mL
Pressure-flow range: 300-1000 cm/h at 22 mm × 20 cm bed and 3 bar
Compression factor: ≤1.05
pH range: 2-13
Maximum pressure: 0.8 MPa
Storage solution: 20% ethanol with stated sodium chloride preservative
Regeneration: 0.5-2 M sodium chloride
Cleaning: 0.1-0.5 M sodium hydroxide or 50% ethanol
Solvent stability: Resistant to acids, alkalis, methanol, ethanol, toluene, DMSO, DMF, and n-heptane

Strong quaternary-amine exchange
≥95 mg/mL BSA capacity
High 300-1000 cm/h flow
Hydrophilic low-binding surface
Rigid low-compression matrix
Broad solvent resistance
Stable large-scale operation
Suitable for diverse biomolecules

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