Seplife LXPM DEAE 5504S Weak Anion-Exchange Medium, 50 µm (CAT#: STEM-BC-3101-ZJF)

This weak anion-exchange medium is designed for high-resolution capture and purification of biological molecules. It uses a polymethyl methacrylate matrix with a hydrophilic surface treatment. Diethylaminoethyl functional groups provide weak anion-exchange selectivity. The 50 µm particles improve chromatographic resolution in demanding separations. A 1000 Å pore structure supports access by antibodies, proteins, peptides, nucleic acids, viruses, and insulin. The rigid matrix provides high mechanical strength and stable packed-bed performance. Low nonspecific adsorption contributes to recovery and process reproducibility. The medium supports salt regeneration and alkaline or ethanol-based cleaning.

Model: Seplife® LXPM DEAE 5504S
Matrix: Polymethyl methacrylate
Appearance: White opaque spherical particles
Functional group: -O-(CH2)2-HN+-(C2H5)2
Ion-exchange type: Weak anion exchange
Exchange capacity: 0.09-0.13 mmol/mL
Average particle size: 50 µm
Pore size: 1000 Å
Binding capacity: ≥90 mg BSA/mL
Pressure-flow range: 300-1000 cm/h at 22 mm × 20 cm bed and 3 bar
Compression factor: ≤1.05
pH range: 2-13
Maximum pressure: 0.8 MPa
Storage solution: 20% ethanol with stated sodium chloride preservative
Regeneration: 0.5-2 M sodium chloride
Cleaning: 0.1-0.5 M sodium hydroxide or 50% ethanol
Solvent stability: Resistant to acids, alkalis, methanol, ethanol, toluene, DMSO, DMF, and n-heptane

High-resolution 50 µm particles
Weak DEAE selectivity
≥90 mg/mL BSA capacity
High-flow polymeric matrix
Low nonspecific adsorption
Strong chemical stability
Low bed compression
Suitable for capture and polishing

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