Seplife LXMS 50Q Strong Anion-Exchange Medium, ≥140 mg BSA/mL (CAT#: STEM-BC-3086-ZJF)

This strong anion-exchange medium is designed for high-capacity purification of biological products. It uses a polystyrene-divinylbenzene matrix with a hydrophilic surface treatment. Quaternary amine groups provide strong anion-exchange functionality. The hydrophilic surface reduces nonspecific adsorption compared with untreated polymeric media. The rigid matrix tolerates high pressure and supports operation at high flow rates. A dynamic binding capacity of at least 140 mg BSA/mL reduces the required packed-bed volume. High resolution supports impurity removal and product-yield improvement. Broad salt tolerance increases process flexibility and simplifies method development. The medium is suitable for monoclonal antibodies, recombinant proteins, vaccines, blood products, viruses, DNA, and peptides.

Model: Seplife® LXMS 50Q
Appearance: White opaque spherical particles, odorless and tasteless
Type: Strong anion-exchange medium
Matrix: Polystyrene-divinylbenzene
Ligand: Quaternary amine
Median particle size d50v: 50 µm
Pressure-flow range: 200-800 cm/h
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common ion-exchange buffers
Ion-exchange capacity: 0.18-0.22 mmol/mL
Dynamic binding capacity: ≥140 mg BSA/mL
Maximum pressure: 30 bar
Test conditions: 10 cm bed height, 25°C, and 0.1 mol/L sodium chloride

Very high BSA binding capacity
Rigid 30-bar matrix
High-flow operation
Hydrophilic low-binding surface
Strong anion-exchange chemistry
Broad CIP pH range
High chromatographic resolution
Salt-tolerant process flexibility

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