Seplife LXPM DEAE 5504M Weak Anion-Exchange Medium, 300-1000 cm/h (CAT#: STEM-BC-3102-ZJF)

This weak anion-exchange chromatography medium is designed for large-scale biomolecule purification. It uses a polymethyl methacrylate matrix with a hydrophilic surface modification. Diethylaminoethyl groups provide weak anion-exchange binding and process selectivity. The 80 µm particle size supports rapid flow and low operating resistance. A 1000 Å pore structure permits access by antibodies, proteins, peptides, oligonucleotides, viruses, and insulin. The rigid particles maintain a stable bed under repeated process cycles. Low nonspecific adsorption helps improve product recovery. The medium is compatible with regeneration by salt and cleaning by sodium hydroxide or ethanol.

Model: Seplife® LXPM DEAE 5504M
Matrix: Polymethyl methacrylate
Appearance: White opaque spherical particles
Functional group: -O-(CH2)2-HN+-(C2H5)2
Ion-exchange type: Weak anion exchange
Exchange capacity: 0.08-0.12 mmol/mL
Average particle size: 80 µm
Pore size: 1000 Å
Binding capacity: ≥90 mg BSA/mL
Pressure-flow range: 300-1000 cm/h at 22 mm × 20 cm bed and 3 bar
Compression factor: ≤1.05
pH range: 2-13
Maximum pressure: 0.8 MPa
Storage solution: 20% ethanol with stated sodium chloride preservative
Regeneration: 0.5-2 M sodium chloride
Cleaning: 0.1-0.5 M sodium hydroxide or 50% ethanol
Solvent stability: Resistant to acids, alkalis, methanol, ethanol, toluene, DMSO, DMF, and n-heptane

High 300-1000 cm/h flow
Weak anion-exchange selectivity
≥90 mg/mL BSA loading
Rigid 80 µm particles
Low nonspecific adsorption
Broad solvent resistance
Low compression factor
Large-scale process suitability

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