Seplife LXPM CM400M Weak Cation-Exchange Medium, 4000 Å (CAT#: STEM-BC-3107-ZJF)

This weak cation-exchange chromatography medium is designed for proteins, antigens, and other biological macromolecules. It uses a hydrophilically modified polymethyl methacrylate matrix. Carboxyl groups provide weak cation-exchange functionality. The 4000 Å pore structure facilitates transport of large molecules through the particles. Uniform pore channels support consistent separation and bed performance. The rigid particles provide high mechanical strength and relatively low backpressure. The stated lysozyme binding capacity is at least 75 mg/mL. Salt regeneration and alkaline or ethanol cleaning support repeated use.

Model: Seplife® LXPM CM400M
Matrix: Polymethyl methacrylate
Appearance: White opaque spherical particles
Functional group: -R-COOH
Ion-exchange type: Weak cation exchange
Exchange capacity: 0.18-0.22 mmol/mL
Average particle size: 80 µm
Pore size: 4000 Å
Binding capacity: ≥75 mg lysozyme/mL
Pressure-flow range: 120-300 cm/h
Long-term pH range: 2-13
Short-term pH exposure: pH 1 or 14 for ≤100 h
Maximum pressure: 0.8 MPa
Storage: 20% ethanol at 4-30°C
Regeneration: 0.5-2 M sodium chloride
Cleaning: 0.1-0.5 M sodium hydroxide or 50% ethanol

Large-pore weak cation exchanger
4000 Å pore structure
≥75 mg/mL lysozyme capacity
Hydrophilic particle surface
Strong mechanical stability
Low backpressure
Wide pH resistance
Reusable after regeneration

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