Seplife LXPM SP 5504S Strong Cation-Exchange Medium, ≥115 mg Lysozyme/mL (CAT#: STEM-BC-3098-ZJF)

This strong cation-exchange chromatography medium is designed for capture, intermediate purification, and polishing of biomolecules. It uses a polymethyl methacrylate matrix with a hydrophilic surface modification. Strong sulfonic-acid ion-exchange groups are bonded to the particle surface. The 50 µm particles provide high chromatographic resolution and stable packed-bed performance. A 1000 Å pore structure supports access by antibodies, proteins, peptides, nucleic acids, viruses, and insulin. The rigid polymer matrix provides high mechanical strength and low nonspecific adsorption. High lysozyme binding capacity supports productive large-scale downstream purification. The medium tolerates common buffers, acids, bases, and compatible organic solvents while strong oxidizing agents should be avoided.

Model: Seplife® LXPM SP 5504S
Matrix: Polymethyl methacrylate
Appearance: White opaque spherical particles
Functional group: -O-R-O-(CH2)3-SO3-
Ion-exchange type: Strong cation exchange
Exchange capacity: 0.09-0.13 mmol/mL
Median particle size d50v: 50 µm
Pore size: 1000 Å
Dynamic binding capacity: ≥115 mg lysozyme/mL
pH range: 2-13
Maximum pressure: 0.8 MPa
Operating temperature: 4-30°C
Storage solution: 20% ethanol with stated sodium chloride preservative
Regeneration: 0.5-2 M sodium chloride
Cleaning: 0.1-0.5 M sodium hydroxide or 50% ethanol
Chemical stability: Common buffers, 1 M acetic acid, 1 M sodium hydroxide, 1 M hydrochloric acid, ethanol, isopropanol, and other compatible solvents

High-resolution 50 µm particles
≥115 mg/mL lysozyme capacity
Strong cation-exchange chemistry
Hydrophilic low-binding surface
Rigid 0.8 MPa matrix
Broad solvent compatibility
Stable large-scale packed beds
Suitable for capture through polishing

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