Recombinant Human BMP-5 Protein, Seafrom (CAT#: STEM-CT-0051-ZJF)

The Recombinant Human BMP-5 Protein manufactured by Seafrom is suitable for involvement in bone and cartilage development and repair.
Transforming growth factor-beta (TGF-β) family members are critical regulatory factors for cell proliferation, differentiation, matrix synthesis, and apoptosis. As their name implies, the BMP (bone morphogenetic protein) family factors initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMP family factors also participate in prenatal development and postnatal growth, remodeling, and maintenance of various other tissues and organs. BMP-5 is expressed in the nervous system, lungs, and liver. It is a regulator of dendritic cell growth in sympathetic neurons. BMP-5 is a 454-amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein.
The lyophilized formulation can be stored at 4°C for 24 months. Once reconstituted, the liquid can be stored at -20°C for 6-12 months, avoiding repeated freeze-thaw cycles.

Expression Host: Human HEK293 Cells
Synonyms: Bone Morphogenetic Protein-5
Protein Sequence: DNA sequence encodes human BMP-5 (NP_066551.1) with an Fc tag at the C-terminus, contains 376 amino acids, predicted molecular weight of 42.6 kD
Purity: ≥95%, analyzed by SDS-PAGE and HPLC
Endotoxin Level: ≤0.01 EU/μg (gel clot method)
Biological Activity: Depends on its ability to induce alkaline phosphatase production in ATDC-5 cells. The expected ED50 efficacy is 1.0-2.0 μg/mL
Purification Method: Chromatographic purification

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

Recombinant Human KGF (FGF-7) Protein, Seafrom
Recombinant Human FGF-8b Protein, Seafrom
Recombinant Human Apo-transferrin Protein, Seafrom
Recombinant Human Holo-Transferrin Protein, Seafrom