In Vivo Flow Cytometry (IVFC) (CAT#: STEM-CBT-0051-WXH)

Name: In Vivo Flow Cytometry (IVFC)
SKU: STEM-CBT-0051-WXH
Rating: 5 (1 reviews)

Introduction

The fluorescence-based in vivo flow cytometry (IVFC) is an emerging tool to monitor circulating cells in vivo. As a noninvasive and real-time diagnostic technology, the fluorescence-based IVFC allows long-term monitoring of circulating cells without changing their native biological environment.
Compared with conventional in vitro flow cytometry, fluorescence-based IVFC can provide biological information of circulating cells without extracting blood from samples, reducing the impact of environment and blood separation processes on experimental results.

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Principle Applications

Principle

After optical transformation and shaping, the laser beam is focused onto a blood vessel. Once a fluorescently labeled target cell (such as a CTC) in the circulatory system passes through the laser focusing point (window), it is excited to generate fluorescence signal, which is collected by the fluorescence receiving system. Then the received fluorescence signals are analyzed by the software, thereby the number of target cells passing through the window per unit time could be obtained.