Analysis of liposomes by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0729-WXH)

Name: Analysis of liposomes by Nanoparticle tracking analysis (NTA)
SKU: STEM-MB-0729-WXH
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Introduction

Liposomes are spherical vesicles made up of biodegradable natural or synthetic phospholipids. They usually have one or more concentric membranes. Liposomes are composed of phospholipids, which are amphipathic and are characterized by having a lipophilic tail and hydrophilic head on the same molecule. Compared with traditional drug delivery systems, liposomes exhibit better properties, including site-targeting, sustained or controlled release, protection of drugs from degradation and clearance, superior therapeutic effects, and lower toxic side effects.

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Principle Applications Procedure Materials

Principle

Nanoparticle tracking analysis (NTA) is a method for visualizing and analyzing particles in liquids that relates the rate of Brownian motion to particle size. The rate of movement is related only to the viscosity and temperature of the liquid; it is not influenced by particle density or refractive index. NTA allows the determination of a size distribution profile of small particles with a diameter of approximately 10-1000 nanometers (nm) in liquid suspension.

Applications

NTA has been used by commercial, academic, and government laboratories working with nanoparticle toxicology, drug delivery, exosomes, microvesicles, bacterial membrane vesicles, and other small biological particles, virology and vaccine production, ecotoxicology, protein aggregation, orthopedic implants, inks and pigments, and nanobubbles.