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α1-acidglycoprotein (α1-acidglycoprotein, AGP or AAG), called serum mucoid (ORM) in the early stage, is a non-specific acute reaction protein, It is also the glycoprotein with the most sugar content (about 45% sugar content) and the most acidic (PI 2.7 ~ 3.5) in human serum. It is mainly produced by liver macrophages and granulocytes. Later studies have found that cancer cells can also be synthesized. AGP serum concentrations can be affected by certain physiological and pathological conditions, such as pregnancy, burns, certain medications, and specific diseases, especially HIV infection. With the increase of age, AGP serum concentration also decreased.
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