The manufacturer of the Unchained Labs Grunt Automated Buffer Prep and Exchange System is Unchained Labs. The GRUNT unchains researchers from the time-consuming, old-school processes for making biologic formulations. Common steps like buffer prep, exchange, dialysis and sample concentration for a formulation screen can take days and it's all manual. With the GRUNT, scientists only spend 20 minutes on set up, picking buffers, entering parameters and loading lab wear. The GRUNT handles everything else. It does all the dirty work so they can focus on the big stuff. The pre-owned products will be thoroughly cleaned and fully tested to perform at manufacturer specifications before shipping.
Application Buffer exchange volume range: Unfilter 24: 0.45-8 mL Unfilter 96: 100-450 μL Formulations: Unfilter 24: Up to 24 formulations in parallel Unfilter 96: Up to 96 formulations in parallel Sample types: Antibodies and other proteins, nucleic acids, lipid nanoparticles (LNPs), adeno-associated viruses (AAVs), virus-like particles (VLPs) Exchange time at full volume (96%, at 10 mg/mL IgG): Unfilter 24: 4.5 hours* Unfilter 96: 3 hours* Protein concentration (range): Up to 200 mg/mL* Target concentration accuracy: ± 10%* Sample recovery: ≥96%* *Sample and formulation dependent.
System Volume measurement: Ultrasonic sensor Exchange pressures: 15, 30 or 60 psi Operating temperature: Room temperature Buffer exchange orbital mixing: Unfilter 24: Optimized at 700 rpm Unfilter 96: Optimized at 875 rpm Duty cycle programmable Physical: 96 cm L x 81.2 cm D x 130 cm H, 220 kg (instrument) 160 cm L x 100 cm D x 198 cm H, 270 kg (instrument and table) Electrical: Voltage 100-260 VAC, 50-60 Hz Nitrogen or CDA requirement: Pressure 0.55–0.9 MPa (80–130 psi) Flow rate 40 L/s (85 cfm) minimum
Features
Hands-off protein formulation with the GRUNT Record every step of the process and cut down on their documentation time In excellent condition Thoroughly cleaned Fully tested to perform at manufacturer specifications