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Study of Protein dynamics by Dielectric spectroscopy (CAT#: STEM-ST-0357-WXH)
Introduction
Protein dynamics and conformational transitions are essential for most biological functions. They are the necessary link to connect atomic-level structural details with cellular processes ranging from enzymatic catalysis to signaling, solute transport, or synaptic transmission.
Principle
The principle of this technique is to apply an AC signal of small amplitude to an electrode immersed into an electrolyte. The initial disturbance (applied) and the response of the electrode is compared by measuring the phase shift of the current and voltage components and by the measurements of their amplitudes.
Applications
Used to study the response of a sample subjected to an applied electric field of fixed or changing frequency. DS describes the dielectric properties of a material as a function of frequency.
Materials
Dielectric spectrometer
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