SP Sepharose XL, 10 L, Cytiva (CAT#: STEM-C-1575-LC)

SP Sepharose XL manufactured by Cytiva is a strong cation exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks. Combining high loading capacities with excellent physical and chemical stability, SP Sepharose XL is ideal for the capture stage of a downstream process, which is characterised by large loads of crude samples. The highly cross-linked, bead formed 6% agarose matrix is hydrophilic, offering low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.

BioProcess resin: Yes
Ligand: Sulphopropyl
Particle size, d50V1: ~90 μm
Ion Exchanger Type: Strong cation exchanger
Matrix: 6% cross-linked agarose with dextran surface extenders
Particle Size: 45 μm-165 μm
Ligand Coupling Method: Dextran extenders through ether bonds
Ionic Capacity: 0.18-0.25 mmol H+/ml medium
pH stability, operational2: 4-13
pH stability, CIP3: 3-14
Pressure/Flow Specification: 300-500 cm/h
Storage: 4 to 30°C, 20% Ethanol + 0.2 M Sodium Acetate
Chemical stability:Commonly used buffers, nonionic detergents, 1 M NaOH, 6 M guanidine hydrochloride
Pack size: 10 L

High loading capacities
High chemical stability
High flow rates

Capto Q ImpRes, 5 L, Cytiva (CAT#: STEM-C-1538-LC)