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Skin Burn Animal Model (CAT#: STEM-AE-0037-WXH)

Introduction

Burns generally refer to skin tissue damage caused by heat (hot liquid, steam, high temperature gas, flame, hot metal, etc.), electric current, chemical substances, radiation and other factors. Research on the pathophysiological changes of burns and new methods of diagnosis and treatment of burns, research and development of new drugs, new materials, and new equipment for burns are inseparable from burn animal model experiments. The ideal model animal for the study of burns is an animal close to human beings in anatomical structure and physiological function. At present, there are various animal models used for burn research, and the establishment technology of thermal burn, chemical burn, electrical burn and radiation burn animal models has been relatively mature.




Applications

• Investigate the mechanisms involved in skin burns.
• Drug development, drug screening and efficacy research.

Procedure

• Thermal burns: hot water burns, steam burns, hot metal burns, electric light source burns, flame burns.
• Electrical burns: burn wounds caused by applying electrodes to the skin of an animal.
• Radiation burns: Exposing an animal's skin to radiation.
• Chemical burns: Apply gauze soaked in a peracid-base solution to the depilated area of the animal.
• Inhalation injury: the use of smoking materials to burn to produce smoke, which is inhaled by experimental animals through the mouth and nose.