Q Seplife XL Strong Anion-Exchange Medium,>160 mg BSA/mL (CAT#: STEM-BC-3155-ZJF)

This strong anion-exchange medium is designed for purification of proteins, nucleic acids, and peptides. It uses highly crosslinked agarose microspheres grafted with dextran tentacles. Quaternary ammonium groups are coupled to the extended dextran chains. The tentacle architecture increases ligand accessibility and available binding area. A BSA adsorption capacity above 160 mg/mL supports high-productivity capture and intermediate purification. The medium provides high linear flow with relatively low backpressure. Low nonspecific adsorption supports strong product recovery. Broad pH and chemical stability permit repeated cleaning and regeneration. The resin is suitable for scale-up in biopharmaceutical and biotechnology manufacturing.

Model: Q Seplife XL
Appearance: White spherical gel, odorless and tasteless
Type: Strong anion-exchange medium
Matrix: Seplife XL microspheres with dextran tentacles
Ligand: Trimethylaminoalkyl quaternary ammonium group
Particle size: 45-165 µm
BSA adsorption capacity:>160 mg/mL
Ion-exchange capacity: 0.18-0.25 mmol/mL
Maximum flow rate: 750 cm/h
Pressure resistance: 0.3 MPa
Operating temperature: 4-30°C
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common aqueous buffers, nonionic detergents, 6 mol/L guanidine hydrochloride, 1 mol/L sodium hydroxide, and 20% ethanol

Ultra-high BSA capacity
Dextran-tentacle structure
Strong quaternary-amine exchange
Up to 750 cm/h flow
Low operating backpressure
Broad CIP pH range
Low nonspecific adsorption
Suitable for process scale-up

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