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Measurement of Serum Viscosity by Rotating Viscometer Method (CAT#: STEM-PPA-0017-YJL)

Introduction

Plasma and serum viscosity measurements have an important role in the clinical management of patients prone to hyperviscosity syndrome. Hyperviscosity syndrome can occur in association with a variety of clinical diagnoses, such as polycythemia, Waldenström macroglobulinemia, multiple myeloma, and leukemia. The viscosity at which symptoms develop is variable, but they rarely appear below a serum or plasma viscosity of 3 cP. Therefore, accurate measurement of serum or plasma viscosity is an important component of patient management.




Principle

The principle of the rotating viscometer method to measure the force acting on a rotor (torque) when it rotates at a constant angular velocity (rotational speed) in a liquid. Rotating viscometers are used for measuring the viscosity of Newtonian (shear-independent viscosity) or non-Newtonian liquids (shear dependent viscosity or apparent viscosity). Rotating viscometers can be divided in 2 groups, namely absolute and relative viscometers. In absolute viscometers the flow in the measuring geometry is well defined.
The measurements result in absolute viscosity values, which can be compared with any other absolute values. In relative viscometers the flow in the measuring geometry is not defined. The measurements result in relative viscosity values, which cannot be compared with absolute values or other relative values if not determined by the same relative viscometer method. Different measuring systems are available for given viscosity ranges as well as several rotational speeds.

Applications

Mineral oil industry; Food industry; Cosmetic/pharmaceutical industry; Petroleum industry; Chemical industry

Procedure

1. Pour the liquid into the measuring cup.
2. Insert the spindle into the liquid.
3. Rotate the spindle and measure the resistance.

Materials

• Sample Type: liquid, gel-like, or semi-solid everyday substances