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Atopic dermatitis (AD) is a chronic skin disorder characterized by itchiness, rashes, and squamous lesions associated with cardiovascular, psychiatric disorders (depression, anxiety, sleep disorders, etc.) and other diseases. In order to better study specific dermatitis, researchers have developed a variety of animal models of specific dermatitis in mice, including (1) AD model caused by enhanced skin sensitization using epithelial sensitive antigens and haptens; (2) AD model of genetically engineered mice; (3) Spontaneous AD mouse model.
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