Immobilized Heparin, 5ml, 786-842, G-BIOSCIENCES (CAT#: STEM-C-3202-LGZ)

G-Biosciences Immobilized Heparin is a purification resin that can be used for a variety of proteins. The resin consists of 6% cross-linked agarose covalently coupled to heparin via an amide bond. The coupling chemistry used results in a highly stable purified resin, the most commonly used stabilizing buffers and denaturants.

Heparin is a linear glycosaminoglycan composed of equimolar amounts of glucosamine and glucuronic acid, linked alternately by α(1→4) glycosidic bonds. Some of its hydroxyl groups are esterified with sulfate groups, and the molecule has a reducing sugar end.

Due to its structure and biochemical role, heparin is able to bind many proteins, enzymes and polycationic organic compounds. Binding is an ionic or more specific protein-ligand or enzyme-inhibitor (or enzyme-activator) interaction.

There are several classes of proteins that bind heparin, including:

Lipoprotein lipase: through ionic interactions
Lipoproteins: LDL, VLDL, VLDL Apo, HDL
Growth hormone
Growth factors: FGF, ECGF
DNA and RNA-related enzymes: polymerases, nucleases, endonucleases
Enzymes: including collagenase, hyaluronidase, lysozyme, protease

Size: 5ml

Boronate Resin (Dry Beads), 50g, 786-315, G-BIOSCIENCES (CAT#-STEM-C-3222-LGZ)
Boronate Resin (Dry Beads), 100g, 786-317, G-BIOSCIENCES (CAT#-STEM-C-3223-LGZ)
Boronate Resin (Suspension), 2ml Resin, 786-823, G-BIOSCIENCES (CAT#-STEM-C-3224-LGZ)
Boronate Resin (Suspension), 10ml Resin, 786-313, G-BIOSCIENCES (CAT#-STEM-C-3225-LGZ)
IgG Binding/ Wash Buffer, 100ml, 786-544, G-BIOSCIENCES (CAT#-STEM-C-3226-LGZ)
IgG Binding/Wash Buffer, 1L, 786-203, G-BIOSCIENCES (CAT#-STEM-C-3227-LGZ)