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GE OligoPilot 400 Oligonucleotide Synthesizer, GE Healthcare (CAT#: STEM-GTPO-0039-ZJF)

Highlights

OligoPilot 400 is used by oligonucleotide pharma and leading suppliers of therapeutic oligonucleotide active pharmaceutical ingredients (APIs) globally.
Seamless scale-up from ÄKTA oligopilot plus and to OligoProcess systems.
Same UNICORN control software as ÄKTA oligopilot and OligoProcess and other BioProcess instruments.

Cat Number: STEM-GTPO-0039-ZJF

Application: To produce hundreds of grams oligonucleotides for early to mid-clinical trials, covering a range of 4 to 60 mmol

Model: GE OligoPilot 400

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Description

The GE OligoPilot 400 Oligonucleotide Synthesizer is manufactured by GE Healthcare.
This instrument was manufactured in 2007 and comes certified with a 90-day warranty.
The GE/Cytiva OligoPilot 400 is designed to produce hundreds of grams oligonucleotides for early to mid-clinical trials, covering a range of 4 to 60 mmol. The production volume is higher than OligoPilot 100, but lower than the OligoPilot 600, OligoPilot 800.
With the speed of coupling, one lot can easily be produced per day. Maintaining well-trained staff, using efficient standard operating procedures (SOPs) and secure supply it can be part of a manufacturing train producing in the range of >50 kg/year. Using shifts the capacity can be multiplied.

Specification

Condition: Certified pre-owned
Application: For production of quantities generally relevant in phase l and phase ll.
Compressed air consumption: 710 Nl/min
Compressed air supply pressure: 6 bar g
Conductivity: Pressure
Depth: 597 mm
Flow rate: 3 pumps delivering up to 400 ml/min with on-line mixing feature; possible to run 1, 2, or all 3 pumps simultaneously giving combined flow
Height: 1220 - 1720 mm (adjustable)
Monomer Inlets: 11
No. of Column Reactors: 1
No. of Waste Outlets: 4
Operating pressure max.: 15 bar
Other Inlets: 9 + 3 ACN
Power Consumption: 110–230 VAC, 50–60 Hz
Protective gas supply pressure: 3 bar g
Recirculation: Yes
Scale: 4 - 60 mmol (calculated for Primer Support 5G)
Storage Conditions: 4°C to 40°CRH: 10 to 95% non-condensedAtmospheric pressure: 84 to 106 kPa (840 to 1060mbar)
UV wavelength: 254 - 700 nm; 1 nm steps; 3 simultaneous wavelengths
Voltage: 110 - 230 VAC
Weight: 204 kg
Width: 1023 mm [m]
Warranty: 90-day warranty

Features

OligoPilot 400 is used by oligonucleotide pharma and leading suppliers of therapeutic oligonucleotide active pharmaceutical ingredients (APIs) globally.
Seamless scale-up from ÄKTA oligopilot plus and to OligoProcess systems.
Same UNICORN control software as ÄKTA oligopilot and OligoProcess and other BioProcess instruments.
Installation and Operation Qualification documentation and performance support are available.
The instrument has change control notification support.

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