Detection of bacterial spores by Coherent Anti-Stokes Raman Spectroscopy (CARS) (CAT#: STEM-ST-0037-WXH)

Name: Detection of bacterial spores by Coherent Anti-Stokes Raman Spectroscopy (CARS)
SKU: STEM-ST-0037-WXH
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Introduction

Bacterial spores are the most dormant form of bacteria since they exhibit minimal metabolism and respiration, as well as reduced enzyme production. Typically, Gram-positive bacteria are best known for producing intracellular spores called endospores as a survival mechanism.

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Principle Applications Procedure Materials

Principle

Coherent Anti-Stokes Raman Spectroscopy (CARS) is a nonlinear Raman spectroscopy technique that uses two very strong collinear lasers to irradiate a sample. The frequency is usually kept constant, with the second laser tuned so that the frequency difference between the two lasers equals the frequency of a Raman-active mode of interest.

Applications

• Analysis of biocompatibility of a material.
• Analysis of nucleic acids.
• Study of interactions between drugs and cells.
• Photodynamic therapy (PDT).
• Analyzing metabolic accumulations of a substance or compounds.
• Diagnosis of disease.
• Analysis of individual cells.
• Cell sorting applications.
• Analyzing the features of biomolecules.
• Study of bone structure.