HPLC Detector / Chromatography Detector

HPLC analysis requires a detector to monitor the compounds themselves in order to quantify and identify the compounds separated in the column. HPLC detectors are capable of determining the identity and concentration of eluting compounds in the mobile phase.There are specific detectors which respond to a specific compound and their response is not dependent on mobile phase composition. Most HPLC detectors work by converting a physiochemical property of an analyte into an electrical signal. Appropriate detectors are selected based on the properties of the target compound and the affinity of the analytical conditions.