Capto SP ImpRes, 10 L, Cytiva (CAT#: STEM-C-1567-LC)

Capto SP ImpRes manufactured by Cytiva is a strong cation exchanger with a high binding capacity, high-flow characteristics and small particle size, ideal for high-throughput intermediate purification and polishing steps of a wide range of biomolecules. This chromatography resin is part of an expanded high-resolution platform based on the high-flow agarose Capto product line. The ability to run at higher flow rates and higher bed heights also increases flexibility in process design.

Chromatography technique: Ion Exchange Chromatography
BioProcess resin: Yes
Ligand: Sulfonate group
Ion Exchanger Type: Strong cation exchanger
Matrix: High-flow agarose
Particle Size: 36-44 μm (d50V)
Binding Capacity/ml Chromatography Medium:> 70 mg lysozyme,> 95 mg BSA
Ionic Capacity: 0.13-0.16 mmol H+/ml medium
pH stability, operational1: 4-12
pH stability, CIP2: 3-14
Pressure/Flow Specification: 300 kPa at min. 220 cm/h, 1 m diameter column, 20 cm bed height
Storage: 4 to 30°C, 20% Ethanol + 0.2 M Sodium Acetate
Chemical stability: Commonly used aqueous buffers, 1 M NaOH, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol and 70 % ethanol
Avoid Using: Oxidizing agents, cationic detergents
Certificate of Analysis: Yes
Pack size: 10 L

Flexible process design due to large operational window of flow rates and bed heights
High throughput purifications easy to optimize and scale-up
Higher manufacturing productivity enables improved process economy
Meets industrial demands for security of supply, robust performance, and regulatory support

Capto MMC, 100 mL, Cytiva (CAT#: STEM-C-1558-LC)